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(+)-Bicuculline CAS:485-49-4



(+)-Bicuculline CAS:485-49-4

Product Name:(+)-Bicuculline

CAS No.:485-49-4


Chemical Name:[R-(R*,S*)]-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)furo[3,4-e]-1,3-benzodioxol-8(6H)-one



Molecular Formula:C20H17NO6

Molecular Weight:367.36

Appearance:White soild

Solubility:Soluble in DMSO

Biological Activity:

Antagonist of the GABAA receptor, (+)-Bicuculline is an antagonist of the GABAA receptor. (+)-Bicuculline is the parent compound of the water soluble N-methyl derivatives (-)-Bicuculline methiodide and (-)-Bicuculline methobromide. Antagonism of the GABAA receptor by (+)-Bicuculline blocks the neurotransmission inhibition function of the GABA system in vitro.


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