Chemleader Biomedical Co., Limited

Order&Service Hotline:

+86(21)5818-0488

Streptozotocin CAS:18883-66-4

2015-07-23

Back

Streptozotocin CAS:18883-66-4

Product Name:Streptozotocin

CAS No.:18883-66-4

Synonyms:Streptozocin;STZ;NSC 85998;Antibiotic U9889;Zanosar

Chemical Name:2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose

Structure:18883-66-4.gif

Purity:≥98% 

Molecular Formula:C8H15N3O7

Molecular Weight:265.2

Appearance:Off-white to pale yellow powder

Solubility:Soluble in water or ethanol

Biological Activity:

Antibiotic and antitumor agent. Alkylates DNA and induces diabetes mellitus via reduction of nicotinamide adenine dinucleotide in pancreatic β-cells in vivo.

References:

1.Weis (1982) Steptozotocin: A review of its pharmacology, efficacy and toxicity. Cancer Treat. Rep. 66 427. PMID: 6277485.

2.Bennett and Pegg (1981) Alkylation of DNA in rat tissues following administration of streptozotocin. Cancer Res. 41 2786. PMID: 6454479.