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Brefeldin A(BFA)

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Catalog No:CL1001 CAS No.:20350-15-6 MDLNo: Formula:C16H24O4 MW:280.36
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Product Overview
Product Name Brefeldin A(BFA)
CAS20350-15-6
FormulaC16H24O4
MW280.36
AppearanceOff-white powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

Brefeldin A (BFA) is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces cancer cell differentiation and apoptosis. It could also improve the HDR(homology-directed repair) efficiency and be an enhancer of CRISPR-mediated HDR. Brefeldin A is also an inhibitor of autophagy and mitophagy.


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