4-Hydroxytamoxifen;(Z)-4-Hydroxytamoxifen; trans-4-Hydroxytamoxifen;(Z)-4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	In-stock	$180.00	Visible after login	- +
10 mg	In-stock	$300.00	Visible after login	- +
25 mg	In-stock	$580.00	Visible after login	- +
50 mg	In-stock	$1000.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

5 mg

In-stock

$180.00

Visible after login

- +

10 mg

In-stock

$300.00

Visible after login

- +

25 mg

In-stock

$580.00

Visible after login

- +

50 mg

In-stock

$1000.00

Visible after login

- +

Product Overview

Product Name	4-Hydroxytamoxifen;(Z)-4-Hydroxytamoxifen; trans-4-Hydroxytamoxifen;(Z)-4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol
CAS	68047-06-3
Formula	C26H29NO2
MW	387.52
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

(E/Z)-4-hydroxy Tamoxifen is an active metabolite of tamoxifen. It is formed from tamoxifen by the cytochrome P450 (CYP) isoform CYP2D6. (E/Z)-4-hydroxy Tamoxifen is cytotoxic to MCF-7 and MDA-MB-231 breast cancer cells (IC50s = 27 and 18 µM, respectively). It also stimulates LC3 lipidation and the formation of autophagic vesicles in MCF-7 cells in a superoxide-dependent manner.

Related literature

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CL1009A

(E)-4-Hydroxytamoxifen/(E)-Afimoxifene

174592-47-3 97%

History

CL1009

4-Hydroxytamoxifen;(Z)-4-Hydroxytamoxifen; trans-4-Hydroxytamoxifen;(Z)-4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol

68047-06-3 98+%

4-Hydroxytamoxifen;(Z)-4-Hydroxytamoxifen; trans-4-Hydroxytamoxifen;(Z)-4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol

Chemical safety data sheet(MSDS)

Certificate Of Authenticity(CPA)