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Streptozotocin; Streptozocin

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Catalog No：CL1016 CAS No.：18883-66-4 MDLNo： Formula：C8H15N3O7 MW：265.22

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
100 mg	In-stock	$230.00	Visible after login	- +
200 mg	In-stock	$400.00	Visible after login	- +

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Product Overview

Product Name	Streptozotocin; Streptozocin
CAS	18883-66-4
Formula	C8H15N3O7
MW	265.22
Appearance	Light yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Streptozotocin (STZ) is a glucosamine-nitrosourea which is commonly used to induce experimental diabetes in animals. It specifically targets beta cells, entering via the glucose transporter GLUT2 and causing alkylation of DNA. DNA damage induces activation of poly ADP-ribosylation, depletion of cellular NAD+ and ATP, and formation of superoxide radicals, leading to the destruction of beta cells.The effectiveness of STZ depends on the level of GLUT2 expression, which in turn may be influenced by age, sex, strain, or species.

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CL1016

Streptozotocin; Streptozocin

18883-66-4 98+%