Product Name | Sorafenib Tosylate |
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CAS | 475207-59-1 |
Formula | C28H24ClF3N4O6S |
MW | 637.03 |
Appearance | White to off-white powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
---|---|---|---|---|
1 g | In-stock | $250.00 | Visible after login | |
5 g | In-stock | $400.00 | Visible after login |
Product Name | Sorafenib Tosylate |
---|---|
CAS | 475207-59-1 |
Formula | C28H24ClF3N4O6S |
MW | 637.03 |
Appearance | White to off-white powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Sorafenib tosylate is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib Tosylate inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib Tosylate induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity.