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Mirdametinib (PD0325901)

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Catalog No:CL1077 CAS No.:391210-10-9 MDLNo: Formula:C16H14F3IN2O4 MW:482.19
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50 mg In-stock $500.00 Visible after login
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100 mg In-stock $1150.00 Visible after login
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Product Overview
Product Name Mirdametinib (PD0325901)
CAS391210-10-9
FormulaC16H14F3IN2O4
MW482.19
AppearanceWhite powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

Mirdametinib, also known as PD-0325901, is a potent bioavailable and selective MEK inhibitor, which targets mitogen-activated protein kinase kinase (MAPK/ERK kinase or MEK) with potential antineoplastic activity. MEK inhibitor PD325901, a derivative of MEK inhibitor CI-1040, selectively binds to and inhibits MEK, which may result in the inhibition of the phosphorylation and activation of MAPK/ERK and the inhibition of tumor cell proliferation. The dual specific threonine/tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors.

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