Home > Category > Signaling Pathways > Metabolism > Cytochrome P450 > Abiraterone Acetate (CB7630)

Abiraterone Acetate (CB7630)

ChemLeader 99+%

Catalog No：CL1079A CAS No.：154229-18-2 MDLNo： Formula：C26H33NO2 MW：391.55

Collect Share

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
250 mg	In-stock	$430.00	Visible after login	- +
500 mg	In-stock	$720.00	Visible after login	- +
1 g	In-stock	$1350.00	Visible after login	- +
5 g	In-stock	$5000.00	Visible after login	- +

Chemical safety data sheet(MSDS)

Download MSDS

Certificate Of Authenticity(CPA)

Download COA

Inquiry Add To Cart

Product Overview
Related documents
Product details
Related literature

Product Overview

Product Name	Abiraterone Acetate (CB7630)
CAS	154229-18-2
Formula	C26H33NO2
MW	391.55
Appearance	White crystalline powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Abiraterone acetate is an inhibitor of the cytochrome P450 (CYP) isoform CYP17A1 (IC50s = 17 and 18 nM for inhibition of C17,20-lyase and 17α-hydroxylase activities, respectively). It is also a prodrug form of abiraterone (Item No.9002768).Abiraterone acetate reduces plasma testosterone levels, increases plasma luteinizing hormone levels, and reduces ventral prostate, seminal vesicle, testis, and kidney weight in mice when administered at doses of 0.1 and 0.5 mmol/kg per day. It also reduces severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load in the culture supernatant of infected Vero E6 cells (EC90 = 8.4 μM) and is active in a plaque reduction assay (EC50 = 1.94 μM). Formulations containing abiraterone acetate have been used in combination therapy for the treatment of metastatic castration-resistant prostate cancer.

Related literature

Sorry, there is no relevant literature

CL1079

Abiraterone (CB-7598)

154229-19-3 99+%

History

CL1079A

Abiraterone Acetate (CB7630)

154229-18-2 99+%