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Tofacitinib Citrate | Tasocitinib Citrate | CP-690550 Citrate

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Catalog No：CL1120A CAS No.：540737-29-9 MDLNo： Formula：C16H20N6O.C6H8O7 MW：504.49

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Product Overview

Product Name	Tofacitinib Citrate \| Tasocitinib Citrate \| CP-690550 Citrate
CAS	540737-29-9
Formula	C16H20N6O.C6H8O7
MW	504.49
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Tofacitinib, also known as tasocitinib, CP-690550, is a Janus kinase (JAK) inhibitor. Tofacitinib modulates the signaling pathway at the point of JAKs, preventing the phosphorylation and activation of STATs. JAK enzymes transmit cytokine signaling through pairing of JAKs (e.g., JAK1/JAK3, JAK1/JAK2, JAK1/TyK2, JAK2/JAK2). Tofacitinib inhibited the in vitro activities of JAK1/JAK2, JAK1/JAK3, and JAK2/JAK2 combinations with IC50 of 406, 56, and 1377 nM, respectively.

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CL1120A

Tofacitinib Citrate | Tasocitinib Citrate | CP-690550 Citrate

540737-29-9 98+%