Product Name | Polmacoxib |
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CAS | 301692-76-2 |
Formula | C18H16FNO4S |
MW | 361.39 |
Appearance | white solid powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
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Product Name | Polmacoxib |
---|---|
CAS | 301692-76-2 |
Formula | C18H16FNO4S |
MW | 361.39 |
Appearance | white solid powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation.