Product Name | VcMMAE; Maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl-monomethyl auristatin E; Mc-Val-Cit-PAB-MMAE |
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CAS | 646502-53-6 |
Formula | C68H105N11O15 |
MW | 1,316.63 |
Storage condition | Avoid light, nitrogen, -20 ℃ |
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Product Name | VcMMAE; Maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl-monomethyl auristatin E; Mc-Val-Cit-PAB-MMAE |
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CAS | 646502-53-6 |
Formula | C68H105N11O15 |
MW | 1,316.63 |
Storage condition | Avoid light, nitrogen, -20 ℃ |
VcMMAE (mc-vc-PAB-MMAE), a MMAE derivative with valine-citrulline (Vc) linker,is an Drug-linker Conjugate for antibody-drug conjugate (ADC) with potent antitumor activity. MMAE is a synthetic antineoplastic agent and can be efficiently released from VcMMAE in vitro and exert cytotoxic activity.