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Lenvatinib | E7080

Catalog No：CL1633 CAS No.：417716-92-8 MDLNo： Formula：C21H19ClN4O4 MW：426.85

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Product Overview

Product Name	Lenvatinib \| E7080
CAS	417716-92-8
Formula	C21H19ClN4O4
MW	426.85
Appearance	Off-white to light yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Lenvatinib is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β in cell-free assays. Lenvatinib (E7080) also inhibits FGFR1-4, PDGFR, Kit (c-Kit), RET (c-RET), and shows potent antitumor activities.

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History

CL1633

Lenvatinib | E7080

417716-92-8 98+%