Product Name | SB 271046 |
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CAS | 209481-20-9 |
Formula | C20H22ClN3O3S2 |
MW | 451.99 |
Storage condition | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
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Product Name | SB 271046 |
---|---|
CAS | 209481-20-9 |
Formula | C20H22ClN3O3S2 |
MW | 451.99 |
Storage condition | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
SB 271046 is a potent, selective and orally active 5-HT6 receptor antagonist with a pKi of 8.92-9.09. SB 271046 show >200-fold selective for the 5-HT6 receptor over other receptors, binding sites and ion channels. SB 271046 has anticonvulsant activity.
Characterization of SB-271046: a potent, selective and orally active 5-HT(6) receptor antagonist.
PMID: 10928964 PMCID: PMC1572216 DOI: 10.1038/sj.bjp.0703457