Product Name | SB 203580 (RWJ 64809) |
---|---|
CAS | 152121-47-6 |
Formula | C21H16FN3OS |
MW | 377.43 |
Appearance | White to light yellow |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
---|---|---|---|---|
20 mg | In-stock | $300.00 | Visible after login | |
50 mg | 3-5days | $500.00 | Visible after login |
Product Name | SB 203580 (RWJ 64809) |
---|---|
CAS | 152121-47-6 |
Formula | C21H16FN3OS |
MW | 377.43 |
Appearance | White to light yellow |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Adezmapimod (SB203580, RWJ 64809, PB 203580) is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM in THP-1 cells, 10-fold less sensitive to SAPK3(106T) and SAPK4(106T) and blocks PKB phosphorylation with IC50 of 3-5 μM. SB203580 induces mitophagy and autophagy.