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SB 203580 (RWJ 64809)

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Catalog No:CL1853 CAS No.:152121-47-6 MDLNo: Formula:C21H16FN3OS MW:377.43
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50 mg 3-5days $500.00 Visible after login
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Product Overview
Product Name SB 203580 (RWJ 64809)
CAS152121-47-6
FormulaC21H16FN3OS
MW377.43
AppearanceWhite to light yellow
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

Adezmapimod (SB203580, RWJ 64809, PB 203580) is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM in THP-1 cells, 10-fold less sensitive to SAPK3(106T) and SAPK4(106T) and blocks PKB phosphorylation with IC50 of 3-5 μM. SB203580 induces mitophagy and autophagy.

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