Product Name | GSK583 |
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CAS | 1346547-00-9 |
Formula | C20H19FN4O2S |
MW | 398.45 |
Appearance | Light yellow to yellow powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
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Product Name | GSK583 |
---|---|
CAS | 1346547-00-9 |
Formula | C20H19FN4O2S |
MW | 398.45 |
Appearance | Light yellow to yellow powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
GSK583 is a highly potent and selective inhibitor of RIP2 kinase with IC50 of 5 nM. GSK583 also inhibits both TNF-α and IL-6 production with IC50 of ~200 nM in explant cultures.