Product Name | Pemetrexed disodium heptahydrate |
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CAS | 357166-29-1 |
Formula | C20H33N5Na2O13 |
MW | 597.48 |
Appearance | White to off-white powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
---|---|---|---|---|
500 mg | In-stock | $125.00 | Visible after login | |
1 g | In-stock | $200.00 | Visible after login | |
5 g | In-stock | $320.00 | Visible after login |
Product Name | Pemetrexed disodium heptahydrate |
---|---|
CAS | 357166-29-1 |
Formula | C20H33N5Na2O13 |
MW | 597.48 |
Appearance | White to off-white powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Pemetrexed disodium heptahydrate (LY231514; HSDB7316; LY-231514; HSDB-7316; Alimta), the heptahydrated disodium salt of Pemetrexed and a pyrimidine-based antifolate, is an antifolate and antimetabolite anticancer medication. It targets TS, DHFR, and GARFT with Ki values of 1.3 nM, 7.2 nM, and 65 nM, in that order. In a variety of tumor types, including malignant mesothelioma, NSCLC (non-small cell lung carcinoma), carcinomas of the breast, colorectum, uterine cervix, head and neck, and bladder, pemetrexed shows strong antitumor activity.