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Nolatrexed dihydrochloride

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Catalog No：CL2163 CAS No.：152946-68-4 MDLNo： Formula：C14H14Cl2N4OS MW：357.26

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5days	$400.00	Visible after login	- +
10 mg	3-5days	$600.00	Visible after login	- +
20 mg	3-5days	$1100.00	Visible after login	- +
50 mg	3-5days	$1650.00	Visible after login	- +

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Product Overview

Product Name	Nolatrexed dihydrochloride
CAS	152946-68-4
Formula	C14H14Cl2N4OS
MW	357.26
Appearance	Light yellow to yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Nolatrexed dihydrochloride (Thymitaq) is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication, DNA damage,S-phase cell cycle arrest, and caspase-dependent apoptosis.This agent also exhibits radiosensitizing activity.

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CL2163

Nolatrexed dihydrochloride

152946-68-4 98+%