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Temozolomide

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Catalog No:CL2164 CAS No.:85622-93-1 MDLNo: Formula:C6H6N6O2 MW:194.15
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Product Overview
Product Name Temozolomide
CAS85622-93-1
FormulaC6H6N6O2
MW194.15
AppearanceOff-white crystalline powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

TMZ(Temozolomide) is a monofunctional SN-1 alkylating agent that can modify nitrogen atoms in the DNA ring and the extracyclic oxygen group, chemically converted to MTIC and degrades to methyldiazonium cation, which transfers methyl groups to DNA at physiologic pH. A DNA damage inducer in L-1210 and L-1210/BCNU cells. Temozolomide induces apoptosis and exhibits antitumor activity.

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