Product Name | Neratinib (HKI-272) |
---|---|
CAS | 698387-09-6 |
Formula | C30H29ClN6O3 |
MW | 557.04 |
Appearance | Pale yellow to white solid |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
---|---|---|---|---|
100 mg | In-stock | $300.00 | Visible after login | |
200 mg | In-stock | $500.00 | Visible after login | |
500 mg | In-stock | $750.00 | Visible after login |
Product Name | Neratinib (HKI-272) |
---|---|
CAS | 698387-09-6 |
Formula | C30H29ClN6O3 |
MW | 557.04 |
Appearance | Pale yellow to white solid |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Neratinib is a highly selective HER2 and EGFR inhibitor with IC50 of 59 nM and 92 nM in cell-free assays; weakly inhibits KDR and Src, no significant inhibition to Akt, CDK1/2/4, IKK-2, MK-2, PDK1, c-Raf and c-Met. Phase 3.