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Navitoclax (ABT-263)

Catalog No：CL2346 CAS No.：923564-51-6 MDLNo： Formula：C47H55ClF3N5O6S3 MW：974.61

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Product Overview

Product Name	Navitoclax (ABT-263)
CAS	923564-51-6
Formula	C47H55ClF3N5O6S3
MW	974.61
Appearance	White to light yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Navitoclax, also known as ABT-263, is an orally bioavailable, synthetic small-molecule antagonist of a subset of the B-cell leukemia 2 (Bcl-2) family of proteins with potential antineoplastic activity. ABT-263 selectively binds to apoptosis suppressor proteins Bcl-2, Bcl-XL, and Bcl-w and prevents their binding to the apoptotic effectors Bax and Bak proteins, which may trigger apoptosis in tumor cells overexpressing Bcl-2, Bcl-XL, and Bcl-w.

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CL2346

Navitoclax (ABT-263)

923564-51-6 98+%