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Pirfenidone (AMR69)

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Catalog No:CL2376 CAS No.:53179-13-8 MDLNo: Formula:C12H11NO MW:197.33
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Product Overview
Product Name Pirfenidone (AMR69)
CAS53179-13-8
FormulaC12H11NO
MW197.33
AppearanceWhite to light yellow powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

Pirfenidone is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II. Pirfenidone has well-established antifibrotic and anti-inflammatory properties in various in vitro systems and animal models of fibrosis. A number of cell-based studies have shown that pirfenidone reduces fibroblast proliferation, inhibits TGF-β stimulated collagen production and reduces the production of fibrogenic mediators such as TGF-β.

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