Product Name | Pirfenidone (AMR69) |
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CAS | 53179-13-8 |
Formula | C12H11NO |
MW | 197.33 |
Appearance | White to light yellow powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
---|---|---|---|---|
500 mg | In-stock | $126.00 | Visible after login | |
1 g | In-stock | $168.00 | Visible after login |
Product Name | Pirfenidone (AMR69) |
---|---|
CAS | 53179-13-8 |
Formula | C12H11NO |
MW | 197.33 |
Appearance | White to light yellow powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Pirfenidone is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II. Pirfenidone has well-established antifibrotic and anti-inflammatory properties in various in vitro systems and animal models of fibrosis. A number of cell-based studies have shown that pirfenidone reduces fibroblast proliferation, inhibits TGF-β stimulated collagen production and reduces the production of fibrogenic mediators such as TGF-β.