Elagolix Sodium; NBI 56418NA; NBI-56418 sodium

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Product Overview

Product Name	Elagolix Sodium; NBI 56418NA; NBI-56418 sodium
CAS	832720-36-2
Formula	C32H29F5N3NaO5
MW	653.57
Appearance	White to light yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Elagolix sodium (NBI56418; ABT-620; Orilissa), the sodium salt of Elagolix, is an orally bioavailable and small molecule antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (KD = 54 pM) approved on 7/23/2018 by FDA for the management of moderate to severe pain associated with endometriosis. Elagolix is a short-acting GnRH antagonist that suppresses ovarian estrogen production in a dose-dependent manner, meaning that higher doses result in full suppression while lower doses only cause partial suppression. Elagolix's non-peptide structure and oral bioavailability make it the leader of a new class of GnRH inhibitors known as second-generation inhibitors.

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History

CL2564A

Elagolix Sodium; NBI 56418NA; NBI-56418 sodium

832720-36-2 98+%

Elagolix Sodium; NBI 56418NA; NBI-56418 sodium

Chemical safety data sheet(MSDS)