Home > Category > Signaling Pathways > Membrane Transporter/Ion Channel > Sodium Channel > Vinpocetine

Vinpocetine

ChemLeader 98+%

Catalog No：CL2571 CAS No.：42971-09-5 MDLNo： Formula：C22H26N2O2 MW：350.45

Collect Share

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Chemical safety data sheet(MSDS)

Download MSDS

Inquiry Add To Cart

Product Overview
Related documents
Product details
Related literature

Product Overview

Product Name	Vinpocetine
CAS	42971-09-5
Formula	C22H26N2O2
MW	350.45
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Vinpocetine (formerly RGH-4405; AY-27,255; AY27,255, RGH4405, TCV-3B, Cavinton, Intelectol; Ethyl apovincaminate) is a synthetic derivative of the vinca alkaloid vincamine which is a natural product extracted from either the seeds of Voacanga africana or the leaves of Vinca minor as well as the lesser periwinkle plant. It is a selective voltage-sensitive sodium channel blocker for the treatment of stroke, vascular dementia and Alzheimer's disease. Vinpocetine has been reported to have a selective and noncompetitive inhibition of Ca2+ PDE and thus regulate cyclic GMP levels in smooth muscle. In addition, vinpocetine has been revealed to inhibit the activities of three resolvable PDE in the cytosol of rat aorta with Ki values of 14±2μM, >1000μM and >1000μM for Ca2+ PDE(+)CaM, cGMP PDE and cAMP PDE, respectively.

Related literature

Sorry, there is no relevant literature

Sorry, no related items

History

CL2571

Vinpocetine

42971-09-5 98+%