Product Name | A 83-01 | A-83-01 |
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CAS | 909910-43-6 |
Formula | C25H19N5S |
MW | 421.52 |
Appearance | Off-white to light yellow powder |
Storage condition | -20°C, protect from light, stored under nitrogen |
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Product Name | A 83-01 | A-83-01 |
---|---|
CAS | 909910-43-6 |
Formula | C25H19N5S |
MW | 421.52 |
Appearance | Off-white to light yellow powder |
Storage condition | -20°C, protect from light, stored under nitrogen |
A-83-01 is a potent inhibitor of TGF-β type I receptor (ALK5-TD) with IC50 of 12 nM. A-83-01 also inhibits the transcription induced by activin/nodal type I receptor (ALK4-TD) and nodal type I receptor (ALK7-TD) with IC50 of 45 nM and 7.5 nM, respectively.
Solutions are unstable and should be fresh-prepared.