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Exatecan Mesylate (DX8951f)

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Catalog No:CL2725A CAS No.:169869-90-3 MDLNo: Formula:C25H26FN3O7S MW:531.55
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Product Overview
Product Name Exatecan Mesylate (DX8951f)
CAS169869-90-3
FormulaC25H26FN3O7S
MW531.55
AppearanceLight yellow to green yellow powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

 Exatecan, also known as DX 8951, is semisynthetic, water-soluble camptothecin derivative with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogues

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