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GNE-9815

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Catalog No：CL2830 CAS No.：2729996-45-4 MDLNo： Formula：C26H22FN5O2 MW：455.48

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Product Overview

Product Name	GNE-9815
CAS	2729996-45-4
Formula	C26H22FN5O2
MW	455.48
Appearance	Off-white to light yellow powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

GNE-9815 (compound 7) is a highly selective, orally bioavailable pan-RAF inhibitor. For CRAF and BRAF, respectively, GNE-9815 displays Ki values of 0.062 and 0.19 nM. The MAPK pathway is modulated synergistically when GNE-9815 and the MEK inhibitor Cobimetinib are combined. Cancers with the KRAS mutation can be studied using GNE-9815.

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CL2830

GNE-9815

2729996-45-4 98+%