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TT16Ainh-A01

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Catalog No：CL2876 CAS No.：552309-42-9 MDLNo： Formula：C19H20N4O3S2 MW：416.52

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Product Overview

Product Name	TT16Ainh-A01
CAS	552309-42-9
Formula	C19H20N4O3S2
MW	416.52
Appearance	White to off-white powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC).

Related literature

Fedigan S, et al. Effects of new-generation TMEM16A inhibitors on calcium-activated chloride currents in rabbit urethral interstitial cells of Cajal. Pflugers Arch. 2017 Nov;469(11):1443-1455.

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CL2876

TT16Ainh-A01

552309-42-9 98+%