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Tivantinib | ARQ-197

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Catalog No:CL2888 CAS No.:905854-02-6 MDLNo: Formula:C23H19N3O2 MW:369.42
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Product Overview
Product Name Tivantinib | ARQ-197
CAS905854-02-6
FormulaC23H19N3O2
MW369.42
AppearanceLight brown to brown powder
Product details

Tivantinib is the first non-ATP-competitive c-Met inhibitor with Ki of 0.355 μM in a cell-free assay, little activity to Ron, and no inhibition to EGFR, InsR, PDGFRα or FGFR1/4. Tivantinib (ARQ 197) induces a G2/M arrest and apoptosis.


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