TH1338

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	3-5days	$396.00	Visible after login	- +
5 mg	3-5days	$856.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

1 mg

3-5days

$396.00

Visible after login

- +

5 mg

3-5days

$856.00

Visible after login

- +

Product Overview

Product Name	TH1338
CAS	1258494-60-8
Formula	C22H21N3O4
MW	391.42
Appearance	Light yellow to yellow powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

TH1338 (compound 3b), an orally active camptothecin derivative and a potent chemotherapeutic agent for cancer, demonstrates excellent cytotoxic potency against human tumor cell lines in vitro. TH1338 (compound 3b) possesses significant brain penetration, favorable efflux pump properties, and hematological toxicity profile.

Related literature

14-Aminocamptothecins: their synthesis, preclinical activity, and potential use for cancer treatment.

PMID: 21341674 DOI: 10.1021/jm101354u

Preparation, Characterization, and In Vivo Study of 7-Ethyl-14-Aminocamptothecin-Loaded Poly(Ethylene Glycol)2000 -Poly(Lactic Acid)2000 Polymeric Micelles Against H460 Human Nonsmall Cell Lung Carcinoma

PMID: 26306026 DOI: 10.1002/jps.24613

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History

CL2901

TH1338

1258494-60-8 98+%

Chemical safety data sheet(MSDS)