HG-9-91-01 | SIK inhibitor 1

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	3-5days	$148.00	Visible after login	- +
5 mg	3-5days	$368.00	Visible after login	- +
10 mg	3-5days	$648.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

1 mg

3-5days

$148.00

Visible after login

- +

5 mg

3-5days

$368.00

Visible after login

- +

10 mg

3-5days

$648.00

Visible after login

- +

Product Overview

Product Name	HG-9-91-01 \| SIK inhibitor 1
CAS	1456858-58-4
Formula	C32H37N7O3
MW	567.68
Appearance	White to yellow powder
Storage condition	White to yellow powder

Product details

HG-9-91-01 is a potent and highly selective salt-inducible kinase (SIK) inhibitor with IC₅₀s of 0.92 nM, 6.6 nM and 9.6 nM for SIK1, SIK2 and SIK3 respectively.

Related literature

Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells.

PMID: 25114223 PMCID: PMC4151730 DOI: 10.1073/pnas.1412308111

The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.

PMID: 25114223 PMCID: PMC4151730 DOI: 10.1073/pnas.1412308111

Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated andregulatory macrophages.

PMID: 23033494 PMCID: PMC3479463 DOI: 10.1073/pnas.1215450109

Sorry, no related items

History

CL2905

HG-9-91-01 | SIK inhibitor 1

1456858-58-4 98+%

HG-9-91-01 | SIK inhibitor 1

Chemical safety data sheet(MSDS)