Home > Category > Signaling Pathways > Immunology & Inflammation > Salt-inducible Kinase (SIK) > YKL-05-099

YKL-05-099

ChemLeader 98+%
Catalog No:CL2906 CAS No.:1936529-65-5 MDLNo: Formula:C32H34ClN7O3 MW:600.11
Size Availability Price(USD) VIP Price (USD) Quantity
1 mg 3-5days $118.00 Visible after login
- +
5 mg 3-5days $506.00 Visible after login
- +
10 mg 3-5days $706.00 Visible after login
- +

Chemical safety data sheet(MSDS)

Download MSDS
  • Product Overview
  • Related documents
  • Product details
  • Related literature
Product Overview
Product Name YKL-05-099
CAS1936529-65-5
FormulaC32H34ClN7O3
MW600.11
AppearanceWhite to light yellow powder
Storage conditionStore in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
Product details

YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. YKL-05-099 binds to SIK1 and SIK3 with IC50s of ~10 and ~30 nM, respectively. YKL-05-099 has slightly less potent SIK2-inhibitory (IC50=40 nM).


Related literature

Development of Chemical Probes for Investigation of Salt-Inducible Kinase Function in Vivo.

PMID: 27224444 PMCID: PMC4992440 DOI: 10.1021/acschembio.6b00217

Related
Sorry, no related items
Service
ChemLeader
021-58180488
Online service time: 9:00-18:00 on weekdays