Deucravacitinib | BMS-986165

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	3-5days	$118.00	Visible after login	- +
5 mg	3-5days	$306.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

1 mg

3-5days

$118.00

Visible after login

- +

5 mg

3-5days

$306.00

Visible after login

- +

Product Overview

Product Name	Deucravacitinib \| BMS-986165
CAS	1609392-27-9
Formula	C20H19D3N8O3
MW	425.46
Appearance	Off-white to light yellow powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases. Which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0 nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain.

Related literature

Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165.

PMID: 31318208 DOI: 10.1021/acs.jmedchem.9b00444

Sorry, no related items

History

CL2962

Deucravacitinib | BMS-986165

1609392-27-9 99+%

Deucravacitinib | BMS-986165

Chemical safety data sheet(MSDS)