Product Name | LY2780301 |
---|---|
CAS | 1226801-23-5 |
Formula | C25H27F4N7O |
MW | 517.52 |
Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
---|---|---|---|---|
1 mg | 3-5days | $248.00 | Visible after login | |
5 mg | 3-5days | $508.00 | Visible after login |
Product Name | LY2780301 |
---|---|
CAS | 1226801-23-5 |
Formula | C25H27F4N7O |
MW | 517.52 |
LY2780301 is a highly selective adenosine triphosphate (ATP)-competitive dual inhibitor of p70S6K and Akt. LY2780301 binds to Akt, inhibiting its activity, which consequently blocks the PI3K/Akt signaling pathway which leads to reduced cell proliferation and the initiation of apoptosis in tumor cells.
PMID: 25902900 DOI: 10.1007/s10637-015-0241-7