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Ailanthone

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Catalog No：HL1349 CAS No.：981-15-7 MDLNo： Formula：C20H24O7 MW：376.40

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Product Overview

Product Name	Ailanthone
CAS	981-15-7
Formula	C20H24O7
MW	376.40
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Ailanthone (Δ13-Dehydrochaparrinone) is a potent inhibitor of both full-length androgen receptor (AR) (IC₅₀=69 nM) and constitutively active truncated AR splice variants (AR_1-651 IC₅₀=309 nM).

Related literature

Ailanthone targets p23 to overcome MDV3100 resistance in castration-resistant prostate cancer.

PMID: 27959342 PMCID: PMC5159881 DOI: 10.1038/ncomms13122

Ailanthone Inhibits Huh7 Cancer Cell Growth via Cell Cycle Arrest and Apoptosis In Vitro and In Vivo.

Sci Rep. 2015 Nov 3;5:16185.

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HL1349

Ailanthone

981-15-7 98+%