Product Name | Ruscogenin |
---|---|
CAS | 472-11-7 |
Formula | C27H42O4 |
MW | 430.62 |
Appearance | White to off-white powder |
Storage condition | 4°C, protect from light |
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Product Name | Ruscogenin |
---|---|
CAS | 472-11-7 |
Formula | C27H42O4 |
MW | 430.62 |
Appearance | White to off-white powder |
Storage condition | 4°C, protect from light |
Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway. Ruscogenin exerts significant anti-inflammatory and anti-thrombotic activities. Ruscogenin has orally bioactivity.
PMID: 27589720 PMCID: PMC5037697 DOI: 10.3390/ijms17091418
PMID: 18946195 DOI: 10.1254/jphs.08083fp