Rosmarinic acid | Labiatenic acid | 迷迭香酸

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Price(USD)

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Quantity

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Product Overview

Product Name	Rosmarinic acid \| Labiatenic acid
CAS	20283-92-5
Formula	C18H16O8
MW	360.31
Appearance	Light yellow to light brown powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Rosmarinic acid (RA, Rosemary acid) is a naturally occurring hydroxylated compound. It has the ability to block complement fixation, inhibit lipoxygenase and cyclooxygenase activity and inhibit the expression of CCL11 and CCR3 by suppressing the IKK-β activity in NF-κB activation signaling. Rosmarinic acid inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively.

Related literature

Rosmarinic acid as a downstream inhibitor of IKK-beta in TNF-alpha-induced upregulation of CCL11 and CCR3.

PMID: 16604092 PMCID: PMC1751564 DOI: 10.1038/sj.bjp.0706728

Rosmarinic Acid Attenuates Cell Damage against UVB Radiation-Induced Oxidative Stress via Enhancing Antioxidant Effects in Human HaCaT Cells.

Biomol Ther (Seoul). 2016 Jan;24(1):75-84.

Combining in vitro and in silico approaches to evaluate the multifunctional profile of rosmarinic acid from Blechnum brasiliense on targets related to neurodegeneration.

Chem Biol Interact. 2016 Jul 25;254:135-45.

Rosmarinic acid suppresses colonic inflammation in dextran sulphate sodium (DSS)-induced mice via dual inhibition of NF-κB and STAT3 activation. Sci Rep.

PMID: 28383063 PMCID: PMC5382778 DOI: 10.1038/srep46252

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History

HL1820

Rosmarinic acid | Labiatenic acid

20283-92-5 98+%

Rosmarinic acid | Labiatenic acid

Chemical safety data sheet(MSDS)