LY294002 HCl | LY294002 hydrochloride

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Size

Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	LY294002 hydrochloride
CAS	934389-88-5
Formula	C19H17NO3·HCl
MW	343.80 \| 307.35
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

LY-294002 hydrochloride (NSC 697286) is a synthetic molecule inhibitor of PI3Kα/δ/β (IC50: 0.5/0.57/0.97 μM, in cell-free assays); more stable than Wortmannin in solution, and also is a blocker of autophagosome formation.

Related literature

Exploring the specificity of the PI3K family inhibitor LY2942002.

PMID: 17302559 PMCID: PMC1868829 DOI: 10.1042/BJ20061489

In vivo and in vitro ovarian carcinoma growth inhibition by a phosphatidylinositol 3-kinase inhibitor (LY2942002).

PMID: 10741711

The in vitro and in vivo effects of 2-(4-morpholinyl)-8-phenyl-chromone (LY2942002), a specific inhibitor of phosphatidylinositol 3'-kinase, in human colon cancer cells.

PMID: 12060641

Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling.

PMID: 17362206 PMCID: PMC1896275 DOI: 10.1042/BJ20070003