Product Name | BIX-01294 hydrochloride hydrate |
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CAS | 1808255-64-2 |
Formula | C28H38N6O2.3ClH.xH2O |
MW | |
Storage condition | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
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Product Name | BIX-01294 hydrochloride hydrate |
---|---|
CAS | 1808255-64-2 |
Formula | C28H38N6O2.3ClH.xH2O |
MW | |
Storage condition | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
BIX-01294 hydrochloride hydrate is a histone-lysine methyltransferase (HMTase) inhibitor, which selective inhibits the G9aHMTase with IC50 of 1.7 μM, reduces histone-3 lysine (9) methylation (H3K9me), induces autophagy and apoptosis in human glioma cells.