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Laduviglusib ( CHIR-99021; CT99021)

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Catalog No:CL1006 CAS No.:252917-06-9 MDLNo: Formula:C22H18Cl2N8 MW: 465.34
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25 mg In-stock $500.00 Visible after login
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50 mg In-stock $800.00 Visible after login
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100 mg In-stock $1500.00 Visible after login
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Product Overview
Product Name Laduviglusib ( CHIR-99021; CT99021)
CAS252917-06-9
FormulaC22H18Cl2N8
MW 465.34
AppearanceOff-white to light brown powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Security information
化学稳定性DMSO中的溶液可在-20°下稳定储存3个月。
Product details

Laduviglusib (CHIR-99021, CT99021) is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively. CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3β compared to CDKs. CHIR99021 functions as a Wnt/β-catenin activator and induces autophagy.


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