Laduviglusib | CHIR-99021

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
10 mg	In-stock	$126.00	Visible after login	- +
25 mg	In-stock	$218.00	Visible after login	- +
50 mg	In-stock	$386.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

10 mg

In-stock

$126.00

Visible after login

- +

25 mg

In-stock

$218.00

Visible after login

- +

50 mg

In-stock

$386.00

Visible after login

- +

Product Overview

Product Name	Laduviglusib \| CHIR-99021 \| CT99021
CAS	252917-06-9
Formula	C22H18Cl2N8
MW	465.34
Appearance	Off-white to light brown powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Security information

化学稳定性	DMSO中的溶液可在-20°下稳定储存3个月。

Product details

Laduviglusib (CHIR-99021, CT99021) is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively. CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3β compared to CDKs. CHIR99021 functions as a Wnt/β-catenin activator and induces autophagy.

Related literature

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