Ruxolitinib phosphate| INCB-018424 phosphate

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Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	Ruxolitinib phosphate\| INCB-018424 phosphate
CAS	1092939-17-7
Formula	C17H18N6·H3PO4
MW	404.36 \| 306.37(free)
Appearance	White to gray powder
Storage condition	4°C, sealed storage, away from moisture

Product details

Ruxolitinib phosphate (INCB018424 phosphate) is a potent JAK1/2 inhibitor with IC₅₀s of 3.3 nM/2.8 nM, respectively, showing more than 130-fold selectivity over JAK3.

Related literature

Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms.

PMID: 20130243 PMCID: PMC3953826 DOI: 10.1182/blood-2009-04-214957

Rationally Repurposing Ruxolitinib (Jakafi (®)) as a Solid Tumor Therapeutic

Front Oncol. 2016 Jun 13;6:142.

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Ruxolitinib sulfate | INCB018424 sulfate

1092939-16-6 98+%

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History

CL2956A

Ruxolitinib phosphate| INCB-018424 phosphate

1092939-17-7 98+%

Chemical safety data sheet(MSDS)